Control | 100 μM Adenosine | Wash | P | |
---|---|---|---|---|
FS interneurons in mPFC (n = 14) | ||||
RMP (mV) | -72.7 ± 0.9 | -72.6 ± 0.9 | 72.3 ± 1.0 | 0.43 |
Input resistance (MΩ) | 171 ± 12 | 175 ± 11 | 182 ± 14 | 0.57 |
Time constant (ms) | 8.6 ± 0.8 | 9.1 ± 0.7 | 10.0 ± 0.5 | 0.52 |
Rheobase (pA) | 184 ± 17 | 196 ± 17 | 179 ± 17 | 0.41 |
LTS interneurons in mPFC (n = 5) | ||||
RMP (mV) | -67.8 ± 1.2 | -67.7 ± 1.2 | - | 0.71 |
Input resistance (MΩ) | 391 ± 64 | 438 ± 70 | 369 ± 43 | 0.17 |
Time constant (ms) | 30.2 ± 5.6 | 41.0 ± 6.6 | 31.2 ± 9.3 | 0.17 |
Rheobase (pA) | 20 ± 6 | 43 ± 10 | 53 ± 14 | 0.06/0.25 |
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Note: Average ± SEM; RMP, resting membrane potential. P lists the results from paired t-tests between control and adenosine. When P < 0.10 the result from the paired t-test between adenosine and wash-out is also given.